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Polygenic score
Influential genes: LBP,GRIK1,TGIF1
Genetic variations in the LBP gene have been connected to its altered levels and the susceptibility to periodontal diseases.
Elevated GRIK1 expression have been seen in inflamed periodontal tissues, that indicates a potential involvement in periodontitis.
Expression of TGIF1 has been found to be upregulated in periodontal tissues of individuals with periodontitis when compared to those who are in a healthy state.
Chronic periodontitis is a chronic inflammation of the gums, caused by the accumulation of large amounts of dental plaque. At first, it may appear with few symptoms of irritation, swelling, and redness, and slowly progress into the chronic stage over time.
A delay in diagnosis may result in severe and irreversible damage directly to the teeth and their supporting structures. Advanced stages can put you at danger of local infections and even systemic complications like sepsis.
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