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Polygenic score
Influential genes: DPP6
According to one GWAS study, the gene DPP6 has been linked to the Risk of Anterior Cruciate Ligament Rupture.
The anterior cruciate ligament is the most injured ligament of the knee. It’s located within the joint cavity connecting the femur and tibia. The ligament is a crucial structure in providing stabilization of the knee by passively holding the knee together.
An ACL injury can happen as a result of getting hit hard on the side of the knee, overextension or twisting of the knee joint. Basketball, football, soccer, and skiing are the sports linked to this type of injury. Studies have shown a slight increased incidence in females.
There are many ways to prevent an ACL injury, but there is no way to cure it once it has occurred. The best you can do to decrease your risk of ACL injury by keeping the muscles surrounding your knees strong and flexible with a consistent workout routine.
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Continue to ShopThere are many ways to prevent an ACL injury, but there is no way to cure it once it has occurred. The best you can do to decrease your risk of ACL injury by keeping the muscles surrounding your knees strong and flexible with a consistent workout routine.
We are currently working on preparing a better list of references and studies. It will be ready soon!