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Observed genes

Polygenic score

Influential genes:  NON-CODING

Variations in the GC gene can influence the levels and activity of VDBP, potentially affecting the availability and distribution of vitamin D.

CYP2R1 is responsible for converting vitamin D into its active form, so any change in this gene may affect the levels of Vitamin D.

Variations in the CYP24A1 genes can impact the efficiency of vitamin D metabolism, leading to alterations in vitamin D levels.

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What is Vitamin D?

Vitamin D is a fat-soluble vitamin that is essential for healthy bone development and structure, immunity and reducing levels of inflammation. The body synthesizes it from cholesterol when the skin is exposed to sunlight, but it is also possible to replenish the body's supply through food or dietary supplements.

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What happens if you don't get enough?

Chronic vitamin D deficiency in children causes rickets, which results in bone deformities and growth disorders. In adults, osteoporosis occurs, leading to frequent fractures and associated pain. Symptoms of severe vitamin D deficiency include fatigue, frequent infections, muscle and joint pain, hair loss and depression.

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Recommendations

The best way to get vitamin D is to stay in the sun, which can cover up to 90% of the recommended daily dose. At the same time, we must not forget to protect ourselves from harmful UV rays. Vitamin D can also be found in certain foods, such as eggs, oily fish and milk. If necessary, dietary supplements can also be considered.

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